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  • دکتری (1394)

    علوم تشریح

    علوم پزشکی تهران، تهران، ایران

  • کارشناسی‌ارشد (1389)

    علوم تشریح

    علوم پزشکی شیراز، شیراز، ایران

  • کارشناسی (1387)

    مامایی

    علوم پزشکی شیراز، شیراز، ایران

  • بیماری های سیستم عصبی مرکزی و محیطی
  • دمیلیناسیون
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    ارتباط

    رزومه

    Effect of Acetamiprid on spatial memory and hippocampal glutamatergic system

    Mohsen Shamsi, Maliheh Soodi, Shirin Shahbazi, Ameneh Omidi
    Journal PapersEnvironmental Science and Pollution Research , 2021 February 1, {Pages 09-Jan }

    Abstract

    Acetamiprid (ACE) is one of the widely used neonicotinoid insecticides. In mammals, in spite of the low-affinity nAChRs, neurotoxic effects following the Acetamiprid exposure have recently been reported, which suggests some concerns regarding the impacts on the nervous system of mammals. This study aims to investigate the effect of Acetamiprid on spatial memory and possible vulnerability of hippocampal glutamatergic system following the Acetamiprid exposure. 10, 20, and 40 mg/kg doses of Acetamiprid were administered to male rats by gavage once per day for 28 days. The spatial memory was examined with the Morris water maze apparatus. The amount of Acetamiprid in the serum and hippocampus was measured. In addition, glutamate level and change

    Quercetin ameliorates acetamiprid-induced hepatotoxicity and oxidative stress

    A Ghazanfari, M Soodi, A Omidi
    Journal Papers , , {Pages }

    Abstract

    Investigating the Role of P-CREB and c-Fos protein Expression in Nicotine-Induced Anxiogenesis in Rats

    M Zarrindast, A Rezayof, M Sahebgharani, SM Tavangar, A Omidi, H Bashiri
    Journal PapersJournal of Babol University of Medical Sciences , Volume 22 , Issue 1, 2020 March 10, {Pages 15-Aug }

    Abstract

    BACKGROUND AND OBJECTIVE: Nicotine is one of the most common addictive substances that has many effects on the central nervous system, including dose-dependent anxiety that is mediated by various proteins. Since the mechanisms and proteins involved in nicotine anxiety are unclear, the purpose of the present study was to investigate the role of p-CREB (cAMP Response Element-Binding Protein) and c-Fos proteins in the basolateral amygdala (BLA) on nicotine-induced anxiety behaviours.METHODS: In this experimental study, 24 male Wistar rats were divided into three groups of 7 (saline, nicotine 0.3 and 0.7 mg/kg, intraperitoneally) in behavioral experiment and four groups of 3 (control: no injection and test, Saline, nicotine 0.3 and 0.7 mg/kg) i

    Extra Pulmonary Manifestations of COVID-19: A Narrative Review

    Ameneh Omidi, Somayeh Shatizadeh Malekshahi, Parsa Veisi
    Journal Papers , Volume 23 , 2020 September 10, {Pages 0-0 }

    Abstract

    Coronaviruses are a large family of viruses that usually cause mild to moderate upper respiratory tract illnesses. The newly emerged sever acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was reported in late 2019 and causes coronavirus disease 2019 (COVID-19). Due to the novelty of the virus, new scientific evidence on various aspects of COVID-19 is reported in the literature continuously. Common symptoms of COVID-19 include fever, dry cough, fatigue, myalgia, arthralgia and Shortness of breath. Some articles have also reported on various manifestations of SARS-CoV-2 infection outside the respiratory tract. The affected organs are gastrointestinal tract, central nervous system, skin, olfactory system, cardiovascular system, liver, kid

    Extrapulmonary Manifestations of Coronavirus Disease 2019: A Narrative Review

    A Omidi, S Shatizadeh Malekshahi, P Veisi
    Journal Papers , , {Pages }

    Abstract

    Dosimetry of Bone-Seeking Radiopharmaceuticals for Palliative Therapy of Bone Metastases: A Simulation Study Using GATE Monte Carlo Code

    S Dalvand, H Rajabi, A Omidi, E Malekzadeh
    Journal Papers , , {Pages }

    Abstract

    Melatonin preconditioning of bone marrow-derived mesenchymal stem cells promotes their engraftment and improves renal regeneration in a rat model of chronic kidney disease

    Kamran Saberi, Parichehr Pasbakhsh, Ameneh Omidi, Maryam Borhani-Haghighi, Saeid Nekoonam, Negar Omidi, Sodabeh Ghasemi, Iraj Ragerdi Kashani
    Journal PapersJournal of molecular histology , Volume 50 , Issue 2, 2019 April 15, {Pages 129-140 }

    Abstract

    Bone marrow-derived mesenchymal stem cells (BMMSCs) transplantation has shown to be effective in treating chronic kidney disease. However, the effectiveness of this strategy is constrained by low homing and survival rate of transplanted cells in the injured organs. Therefore, developing strategies to improve homing and cell survival rate and therapeutic potential in cell-based therapies seems necessary. The purpose of this study is to evaluate the effect of pretreating BMMSCs with melatonin (MT) on the prosurvival and renoprotective of transplanted cells into the irreversible model of unilateral ureteral obstruction. Adult male Sprague–Dawley rats were randomized into four groups: Sham, UUO, UUO + BMMSCs, and UUO + BM

    Effect of pretreatment with intracerebroventricular injection of minocycline on morphine‐induced memory impairment in passive avoidance test: role of P‐CREB and c‐Fos?…

    Shokouh Hamidkhaniha, Hamideh Bashiri, Ameneh Omidi, Ali Hosseini‐Chegeni, Seyed Mohammad Tavangar, Salehe Sabouri, Hamed Montazeri, Mousa Sahebgharani
    Journal PapersClinical and Experimental Pharmacology and Physiology , 2019 March 28, {Pages }

    Abstract

    Minocycline as a member of tetracycline family is a lipophilic broad‐spectrum antibiotic, which can display some non‐antibiotic properties such as antioxidant, antiapoptosis, neuroprotection and modulation of pharmacological traits of drugs of abuse (ie., reward, sensitization and/or analgesia). Thus, the aim of the present study was to investigate the effect of Intracerebroventricular (ICV) injection of minocycline on morphine‐induced memory impairment and motor function in male Wistar rats. The behavioral responses were measured by passive avoidance test for evaluating memory, and open field for studying motor function. Furthermore, the expression of Phospho‐cAMP response element‐binding protein (P‐CREB) and c‐Fos were asse

    Ellagic acid reduces methotrexate-induced apoptosis and mitochondrial dysfunction via up-regulating Nrf2 expression and inhibiting the IĸBα/NFĸB in rats

    Reihaneh Ebrahimi, Mohammad Reza Sepand, Seyed Afshin Seyednejad, Ameneh Omidi, Mostafa Akbariani, Maryam Gholami, Omid Sabzevari
    Journal PapersDARU Journal of Pharmaceutical Sciences , Volume 27 , Issue 2, 2019 December 1, {Pages 721-733 }

    Abstract

    Background The clinical application of methotrexate (MTX), an efficacious cytotoxic drug, is restricted due to its associated liver toxicity. Ellagic acid (EA), a natural polyphenol, possesses hepatoprotective, antioxidant and anti-inflammatory properties. Objectives The present study seeks to address the hepatoprotective effects of Ellagic acid (EA) against MTX-mediated oxidative stress (OS) and widen our current knowledge of the underlying molecular mechanisms of MTX toxicity. Methods Wistar rats were orally given EA (5?mg/kg and 10?mg/kg) for 10 successive days and at the end of the third day they were administered a single dose of MTX (20?mg/kg i.p). Results After performing biochemical analysis, liver enzymes and malondialdehyd

    Effect of pretreatment with intracerebroventricular injection of minocycline on morphine‐induced memory impairment in passive avoidance test: Role of P‐CREB and c‐Fos …

    S Hamidkhaniha, H Bashiri, A Omidi, A Hosseini‐Chegeni, SM Tavangar, ...
    Journal Papers , , {Pages }

    Abstract

    Preconditioning with SDF-1 Improves Therapeutic Outcomes of Bone marrow-derived Mesenchymal Stromal Cells in a Mouse Model of STZ-induced Diabetes

    Mohammad Sadegh Gholami Farashah, Parichehr Pasbakhsh, Ameneh Omidi, Saied Nekoonam, Roya Aryanpour, Iraj Regardi Kashani
    Journal PapersAvicenna Journal of Medical Biotechnology , Volume 11 , Issue 1, 2018 December 22, {Pages 35-42 }

    Abstract

    Background: Nowadays, transplantation of bone marrow-derived Mesenchymal Stromal Cells (BMSCs) is currently an important alternative therapy for patient’s type 1 diabetes mellitus. But a number of critical obstacles lie ahead of this new strategy including reducing stem cell homing to the damaged tissue due to oxidative stress. The purpose of the present study was to investigate whether preconditioning of BMSCs with SDF-1 could enhance their homing to the pancreas and promote regeneration of the pancreatic β cells after being intravenously injected.Methods: Mice BMSCs were isolated and expanded. Cell proliferation was assayed by MTT Assay. Preconditioning was performed with 10 ng/ml SDF-1α for 24 hr. Male NMRI mice were injected with hi

    Acetyl-l-carnitine attenuates arsenic-induced liver injury by abrogation of mitochondrial dysfunction, inflammation, and apoptosis in rats

    Vida Bodaghi-Namileh, Mohammad Reza Sepand, Ameneh Omidi, Mehdi Aghsami, Seyed Afshin Seyednejad, Sara Kasirzadeh, Omid Sabzevari
    Journal PapersEnvironmental toxicology and pharmacology , Volume 58 , 2018 March 1, {Pages 20-Nov }

    Abstract

    Industrial and agricultural developments in recent years have resulted in the excessive discharge of arsenic into the environment, making arsenic toxicity a major worldwide concern. Oxidative stress is considered the primary mechanism for arsenic toxicity. The main objective of this study was to evaluate acetyl-l-carnitine’s (ALC) protective ability against the arsenic-induced hepatotoxicity. For this purpose, male Wistar rats were distributed randomly into 5 groups of 8 rats each: control, arsenic (5 mg/kg) and arsenic plus ALC (5 mg/kg; 100, 200, 300 mg/kg). The animals were gavaged for 21 consecutive days. Liver tissue samples were extracted 24 h after the last treatment and were later analyzed for biochemical and histological

    Protective effects of erythropoietin against cuprizone-induced oxidative stress and demyelination in the mouse corpus callosum

    Iraj Ragerdi Kashani, Hossein Chavoshi, Parichehr Pasbakhsh, Mahmoud Hassani, Ameneh Omidi, Reza Mahmoudi, Cordian Beyer, Adib Zendedel
    Journal PapersIranian journal of basic medical sciences , Volume 20 , Issue 8, 2017 August , {Pages 886 }

    Abstract

    Objective (s):Increasing evidence in both experimental and clinical studies suggests that oxidative stress plays a major role in the pathogenesis of multiple sclerosis. The aim of the present work is to investigate the protective effects of erythropoietin against cuprizone-induced oxidative stress.Materials and Methods:Adult male C57BL/6J mice were fed a chow containing 0.2% cuprizone for 6 weeks. After 3 weeks, mice were simultaneously treated with erythropoietin (5,000 IU/kg body weight) by daily intraperitoneal injections.Results:Our results showed that cuprizone induced oxidative stress accompanied with down-regulation of subunits of the respiratory chain complex and demyelination of corpus callosum. Erythropoietin antagonized these eff

    Inductive Role of Sustentacular Cells (Sertoli Cells) Conditioned Medium on Bone Marrow Derived Mesenchymal Stem Cells

    Mahdieh Hajian Monfared, Mohammad Akbari, Somayeh Solhjoo, Heidar Tooli, Ameneh Omidi, Freshteh Aliakbari, Sahar Ijaz, Tahmineh Mokhtari, Tayebeh Rastegar
    Journal PapersInternational Journal of Morphology , Volume 35 , Issue 4, 2017 December , {Pages 1597-1606 }

    Abstract

    HAJIAN MONFARED, Mahdieh et al. Inductive Role of Sustentacular Cells (Sertoli Cells) Conditioned Medium on Bone Marrow Derived Mesenchymal Stem Cells. Int. J. Morphol.[online]. 2017, vol. 35, n. 4, pp. 1597-1606. ISSN 0717-9502. http://dx. doi. org/10.4067/S0717-95022017000401597.

    Protective effects of cannabidiol on cuprizone-induced demyelination in C57BL/6 mice

    Maryam Sajjadian, Iraj Ragerdi Kashani, Parichehr Pasbakhsh, Mahmoud Hassani, Ameneh Omidi, Nasrin Takzare, Tim Clarner, Cordian Beyer, Adib Zendedel
    Journal PapersJournal of Contemporary Medical Sciences , Volume 3 , Issue 11, 2017 September 26, {Pages 278-283 }

    Abstract

    Objective Experimental and clinical studies suggest that oxidative stress plays an important role in the pathogenesis of multiple sclerosis. In this study, we have investigated the effects of the non-psychoactive cannabinoid cannabidiol (CBD), which exerts antioxidant effects and has recently been approved for the treatment of inflammation, pain, and spasticity associated with MS patients and in a MS mouse model, ie cuprizone-induced demyelination. Methods Adult male BL/6 mice were fed with 0.2% cuprizone for 5 weeks, which caused severe demyelination of the corpus callosum (CC). Animals were simultaneously treated with 5 mg? kg− 1 CBD by daily intra-peritoneal injections. Using immunohistochemistry and transmission electron microscope, w

    Resveratrol pretreatment enhanced homing of SDF-1α-preconditioned bone marrow-derived mesenchymal stem cells in a rat model of liver cirrhosis: resveratrol & SDF-1α?…

    Ragerdi Kashani I. Hajinejad M, Pasbakhsh P, Omidi A, Mortezaee K, Nekoonam s, Mahmoudi R
    Journal PapersJournal of Cellular Biochemistry , 2017 November , {Pages }

    Acetyl-L-Carnitine Attenuates Arsenic-Induced Oxidative Stress and Hippocampal Mitochondrial Dysfunction

    Omid Sabzevari Hedieh Keshavarz-Bahaghighat, Mohammad Reza Sepand, Mohammad Hossein Ghahremani, Mehdi Aghsami, Nima Sanadgol, Ameneh Omidi, Vida Bodaghi-Namileh
    Journal PapersBiological Trace Element Research , 2017 November 30, {Pages }

    Resveratrol pretreatment enhanced homing of SDF-1α-preconditioned bone marrow-derived mesenchymal stem cells in a rat model of liver cirrhosis: resveratrol & SDF-1α …

    RKI Hajinejad M, Pasbakhsh P, Omidi A, Mortezaee K, Nekoonam s, Mahmoudi R
    Journal Papers , , {Pages }

    Abstract

    Effect of acetyl-L-carnitine on antioxidant status, lipid peroxidation, and oxidative damage of arsenic in rat

    Mohammad Reza Sepand, Kamal Razavi-Azarkhiavi, Ameneh Omidi, Mohammad Reza Zirak, Samin Sabzevari, Ali Reza Kazemi, Omid Sabzevari
    Journal PapersBiological trace element research , Volume 171 , Issue 1, 2016 May 1, {Pages 107-115 }

    Abstract

    Arsenic (As) is a widespread environmental contaminant present around the world in both organic and inorganic forms. Oxidative stress is postulated as the main mechanism for As-induced toxicity. This study was planned to examine the protective effect of acetyl-l-carnitine (ALC) on As-induced oxidative damage in male rats. Animals were randomly divided into four groups of control (saline), sodium arsenite (NaAsO2, 20?mg/kg), ALC (300?mg/kg), and NaAsO2 plus ALC. Animals were dosed orally for 28 successive days. Blood and tissue samples including kidney, brain, liver, heart, and lung were collected on the 28th day and evaluated for oxidative damage and histological changes. NaAsO2 exposure caused a significant lipid peroxidatio

    Evaluation of simvastatin and bone marrow-derived mesenchymal stem cell combination therapy on airway remodeling in a mouse asthma model

    Maryam Mohammadian, Hamid Reza Sadeghipour, Iraj Ragerdi Kashani, Gila Pirzad Jahromi, Amene Omidi, Amir Kavian Nejad, Ravie Golchoobian, Mohammad Hossein Boskabady
    Journal PapersLung , Volume 194 , Issue 5, 2016 October 1, {Pages 777-785 }

    Abstract

    Introduction The effect of bone marrow-derived mesenchymal stem cells (BMSCs) on asthma treatment was shown in our previous study. Several studies have shown the effect of statins on BMSC preservation and migration to sites of inflammation. In this study, the effects of simvastatin and BMSC combination therapy in an ovalbumin-induced asthma model in mouse were examined. Methods Four groups of BALB/c mice were studied including control group (animals were not sensitized), asthma group (animals were sensitized by ovalbumin), asthma?+?simvastatin group (asthmatic animals were treated with simvastatin), and asthma?+?BMSC?+?simvastatin g

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    دروس نیمسال جاری

    • دكتري
      علوم تشريحي ( واحد)
      دانشکده علوم پزشکی، گروه انگل شناسي
    • دكتري
      علوم تشريحي ( واحد)
    • دكتري
      آناتومي سطحي ( واحد)
    • دكتري
      آناتومي سطحي ( واحد)
    • دكتري
      تكنيكهاي پيشرفته ميكروآناتومي ( واحد)
    • دكتري
      تكنيكهاي پيشرفته ميكروآناتومي ( واحد)
    • دكتري
      آناتومي مقاطع بدن ( واحد)
    • دكتري
      آناتومي مقاطع بدن ( واحد)
    • كارشناسي ارشد
      كالبدشناسي سر و گردن ( واحد)
    • كارشناسي ارشد
      كالبدشناسي سر و گردن ( واحد)
    • كارشناسي ارشد
      كارآموزي 1 ( واحد)
    • كارشناسي ارشد
      كشت سلولي ( واحد)
    • كارشناسي ارشد
      كشت سلولي ( واحد)

    دروس نیمسال قبل

    • كارشناسي ارشد
      تكنيكهاي ماكرو و ميكرو آناتومي ( واحد)
      دانشکده علوم پزشکی، گروه علوم تشريح
    • كارشناسي ارشد
      تكنيكهاي ماكرو و ميكرو آناتومي ( واحد)
    • كارشناسي ارشد
      علوم تشريح اندام ( واحد)
    • كارشناسي ارشد
      علوم تشريح اندام ( واحد)
    • كارشناسي ارشد
      كارورزي ( واحد)
    • كارشناسي ارشد
      تكنيكهاي پيشرفته علوم تشريحي ( واحد)
    • كارشناسي ارشد
      تكنيكهاي پيشرفته علوم تشريحي ( واحد)
    • كارشناسي ارشد
      كالبدشناسي تنه ( واحد)
    • كارشناسي ارشد
      كالبدشناسي تنه ( واحد)
    • كارشناسي ارشد
      تكنيك هاي ماكرو و ميكرو آناتومي ( واحد)
    • كارشناسي ارشد
      تكنيك هاي ماكرو و ميكرو آناتومي ( واحد)
    • كارشناسي ارشد
      نوروآناتومي ( واحد)
    • كارشناسي ارشد
      نوروآناتومي ( واحد)
    • دكتري
      نوروآناتومي و نوروفيزيولوژي ( واحد)
    • 1399
      ذوالفقاري, امين
      اثرات آنتي اكسيدان هدفمند ميتوكندري SkQ1 بر رميليناسيون در مدل موشي دميلينه شده با كوپريزون
    • 1398
      ميراب, سيد محمدهادي
      اثرات اگزوزوم هاي مشتق از سلول‌هاي پيش‌ساز اليگودندروسيتي ِتمايزيافته از سلولهاي بنيادي پرتوان القايي بر رميليناسيون در مدل موشي ِالقاءشده با كوپريزون
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